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Image Credit: Christine Daniloff/MIT

Researchers cured mice of a rare liver disorder caused by a single genetic mutation using CRISPR-cas9

Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation.  Incoming search terms:yhs-fullyhosted_003
mouse dual gRNA targeting

Dual sgRNAs facilitate CRISPR/Cas9 mediated mouse genome targeting

The bacterial CRISPR/Cas9 system has been shown recently to be a versatile RNA-guided mammalian genome modification system. One-step generation of mouse genome targeting has been achieved ...
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Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

A group led by Kate O’Connor-Giles from University of Wisconsin recently demonstrated that the readily programmable CRISPR/Cas9 system
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Researchers developed a method to create a comprehensive library of mutations across all genes in the mouse genome.

Researchers have developed a method to create a comprehensive library of mutations across all genes in the mouse genome.
PowerPoint Presentation

Efficient genome editing in zebrafish using a CRISPR-Cas system.

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems have evolved in bacteria and archaea as a defense mechanism to silence foreign nucleic ...
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