List/Grid Tag Archives: featured

CRISPR Biological Tape: Recording Cellular Events Over Time

Synthetic biologists have previously used CRISPR to store poems, books, and images in DNA, but now researchers for the first time used CRISPR to record cellular activity and the timing ...

A Molecular Switch for CRISPR: Anti-CRISPR

For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided “immune system” called CRISPR-Cas.

CRISPR-mediated gene editing using small molecules

One of the most exciting scientific advances made in recent years is CRISPR—the ability to precisely edit the genome of cells.

Guide-Seq: Genome-wide off-target cleavage sites of CRISPR-Cas nucleases

Massachusetts General Hospital (MGH) investigators have developed a method of detecting, across the entire genome of human

New way to turn genes on using CRISPR-Cas9

Using a gene-editing system originally developed to delete specific genes, MIT researchers have now shown that they can
steptococcus pyogens

The many faces of the bacterial defense system

Even bacteria have a kind of “immune system” they use to defend themselves against unwanted intruders – in their case,

Broad Institute gets first patent on revolutionary CRISPR-Cas9 system

The Broad Institute today announced that the United States Patent and Trademark Office has issued the first patent for an

Researchers reveal structure of key CRISPR complex

Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first high definition

Researchers show expanded role for guide RNA in Cas9 interactions with DNA

The potential is there for bacteria and other microbes to be genetically engineered to perform a cornucopia of valuable

Mystery of how Cas9 Targets and Cleaves DNA solved.

A central question has been answered regarding a protein that plays an essential role in the bacterial immune system and is fast becoming a
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