List/Grid CRISPR Technology

steptococcus pyogens

The many faces of the bacterial defense system

Even bacteria have a kind of “immune system” they use to defend themselves against unwanted intruders – in their case,

Broad Institute gets first patent on revolutionary CRISPR-Cas9 system

The Broad Institute today announced that the United States Patent and Trademark Office has issued the first patent for an

Cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

RNA-guided endonucleases (RGENs) derived from the CRISPR/Cas system represent an efficient tool for genome editing. RGENs consist of two components: Cas9 protein and guide RNA. Plasmid-mediated ...

Researchers reveal structure of key CRISPR complex

Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first high definition

Researchers show expanded role for guide RNA in Cas9 interactions with DNA

The potential is there for bacteria and other microbes to be genetically engineered to perform a cornucopia of valuable

Mystery of how Cas9 Targets and Cleaves DNA solved.

A central question has been answered regarding a protein that plays an essential role in the bacterial immune system and is fast becoming a

Shortening guide RNA significantly improves specificity of CRISPR-Cas nucleases

A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. In a report receiving advance online publication in Nature Biotechnology, Massachusetts General ...

Antibiotic ‘smart bomb’ can target specific strains of bacteria using CRISPR-cas

Researchers from North Carolina State University have developed a de facto antibiotic “smart bomb” that can identify specific strains of

Researchers achieved precise gene modification in monkeys using CRISPR-cas9

Monkeys are important for modeling diseases because of their close similarities to humans, but past efforts to precisely modify genes in

CRISPR declared as Science ” 2013 Breakthrough of the year” runner up.

The annual list of groundbreaking scientific achievements, selected by Science and its international nonprofit publisher, AAAS, includes the genome-editing tool, CRISPR-cas as second ...
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